Large Enterprises have a huge opportunity to accelerate their business by applying SAFe® and DevSecOps practices. SAFe provides guidance to organize around value, improve quality, reduce lead time, increase employee satisfaction, and apply Lean-Agile principles and values. This article provides further guidance to succeed with your DevOps implementation. It describes how you can practically apply shift-left practices with the ‘DevOps Evolution Model’ and how you can eliminate bottlenecks in your DevOps pipeline by applying CI/CD pipeline modeling. To reduce cognitive overload and to improve productivity, it presents a software factory and the value of standard engineering services. Finally, as security becomes even more critical to software development, we show how to apply discussed approaches for a successful DevSecOps implementation.